Search results for " Viral gastroenteritis"

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Lineage diversification and recombination in type-4 human astroviruses.

2013

Abstract Human astroviruses (HAstVs) are important enteric pathogens and can be classified genetically and antigenically into eight types. During surveillance of HAstVs in Italy, type-4 HAstVs were detected only sporadically and found to cluster into two distinct genetic groups. Upon sequence analysis of the 3′ end of the polymerase gene (ORF1b) and of the full-length ORF2, the 2008 type-4 HAstV strains were characterised as a novel ORF2 genetic lineage, designated as 4c. The 2008 type-4 HAstVs also shared the ORF1b gene with similar HAstV-4c strains detected globally, thus displaying a conserved ORF1b/ORF2 asset. By interrogation of the databases, this novel lineage 4c accounted for 60.8% …

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaLineage (genetic)Sequence analysisMolecular Sequence DataSequence alignmentBiologyMicrobiologyAstrovirusFecesOpen Reading FramesAstrovirus Epidemiology Genotyping Italy Viral gastroenteritisPhylogeneticsAstroviridae InfectionsGenetic variationGeneticsHumansAmino Acid SequenceMolecular BiologyGenotypingGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsRecombination GeneticBase SequenceSequence Homology Amino AcidSequence Analysis RNAvirus diseasesGenetic Variationbiology.organism_classificationRNA-Dependent RNA PolymeraseGastroenteritisInfectious DiseasesRNA ViralCapsid ProteinsSequence AlignmentMamastrovirusInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
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